# forskning på agouti
Author: Nonimonos

Det kom ett mycket trevligt mail till fifes genetilista (en maillista)

  
Forskning har kommit fram till det vi många har trott att kattens agoutimönster är påverkat av tre olika locus

  
Dominant Mackarel TaTa,  
Bärare utav classic Tata,  
Reccensiv classic tata.

  
Dominant Tickat TiTi  
Bärare utav Tick Titi  
utan tick titi

Dominant spottat SpSP  
bärare utav spottat Spsp  
utan spottar spsp

  
Detta gör mig mycket glad då mina strävansmål i min mönsteravel stämmer bra då.  
Jag var inte helt ute och cyklade - jag var helt på rätt spår.

  
Tror jag fick detta rätt nu, eller Dagny vad säger du?

Fan vilken dag detta är - inte bara detta i min mailbox, utan jag har blivit erbjuden två jobb samma dag också - inte klokt!

## Comment 1
Author: alltidsiames

Jag önskar verkligen att jag förstod detta! Och att jag också fick jobb. Grattis!![Skrattande](http://www.siames.ifokus.se/tiny3/plugins/emotions/img/smiley-laughing.gif "Skrattande")

## Comment 2
Author: Nonimonos

Jag som tyckte jag "översatte" forskningsrapporten till förståerlig svenska :-)

Jag ska se om jag fixar redogöra för det närmare - så svårt är det inte att förstå, men nu måste jag iväg och handla så det får bli senare.

## Comment 3
Author: marieirene

2 jobb ![Glad](http://siames.ifokus.se/tiny3/plugins/emotions/img/smiley-smile.gif "Glad") Inte illa.  Båda lika bra? Du får dra lott kanske.. ?

## Comment 4
Author: Liilu

I'm not sure I understand the Swedish - would you be able to put this in English?

## Comment 5
Author: Liilu

Well I see the basics of the genetics of a patterned cat but not sure of the mackerel and classic together?

It's always nice to find a dominant patterned cat - I am hoping Maude is - however - how does this influence the quality of the pattern? Or did they mean that you are going to get all patterned kittens with a dominant cat?

## Comment 6
Author: Avenacattery

@5 It is easier to read in the full text on-line:

[http://www.genetics.org/cgi/content/full/184/1/NP](http://www.genetics.org/cgi/content/full/184/1/NP)

dominant patterned cat... Now I think you have to explain you selvs?

I belive the sience of this is exactly as they put it in the article...

## Comment 7
Author: saiii

Om jag har fattat rätt nu, så kan agouti antingen vara dominant eller recisivt? Eller fattade jag fel? Kan verkligen inte mycket om kattens genetik.... ![Tungan ute](http://siames.ifokus.se/tiny3/plugins/emotions/img/smiley-tongue-out.gif "Tungan ute")

## Comment 8
Author: Liilu

Yes you can have a dominant patterned cat. I have put a little example below - Agouti (A) - pattern and non-agouti - self (a).

AA would be dominant pattern and Aa would be patterned but carry non agouti (self) and aa would be self.

1) Therefore, if you put a cat who is dominant AA to a self aa, you would get 100% non dominant patterned cats Aa.

2) If you put a dominant AA to a non dominant pattern Aa you would get all patterned but only half dominant.

3) If you put a non dominant pattern Aa to a self aa, you would get half self and half patterned and no dominant pattern.

I have drawn a little picture to illustrate these types.

And thank you for the link!

## Comment 9
Author: Nonimonos

Nu handlar inte forskningen om dominant (homozygot) agouti eller inte. Det är något som redan är utrett. Det går bra att DNA testa om katten är det eller ej - frågan är mer vilket/vilka agoutimönster den bär.

In english. It is not about agouti or not agouti. It is about what agoutipattern that they carries. This is absolutly something that get the patterns to be better if breeding is doing right.

## Comment 10
Author: Liilu

Better because the pattern has a dominant genotype? or? I looked at the abstract as I don't have full access so I don't really grasp how the different dominance of the specific types of patterns has any baring on the quality of the pattern. I see that between the patterns they may have found the different loci responsible, but I don't see the bit where the dominance fits in - maybe this is in the full text? Can you explain it further lina?

## Comment 11
Author: Liilu

And how does mackerel fit with classic in your bit above? I'm still stuck on this.

## Comment 12
Author: saiii

Hm.. det här kommer ta tid att förstå! ![Tungan ute](http://siames.ifokus.se/tiny3/plugins/emotions/img/smiley-tongue-out.gif "Tungan ute")

## Comment 13
Author: Liilu

Well being a doctor is useful for something I suppose - managed to log in with my account and download it - I shall have a little read :o)

## Comment 14
Author: Liilu

Lovely article! I see where you got your mackerel and classic from. Let hope he does some more testing - two cats is a little thin on the ground!

## Comment 15
Author: Avenacattery

Oh sorry. Thought it was on open access... Yes it is helpful downloading articles from work ;)

Anyhow, I know about the agouti non agouti. Just thought you meant something else.

You mention two cats. Do not know if you refer to the article or not ("Let hope he does some more testing" who is this he that you refer to?). If you do refer to the article you have to precise why you consider it thin. I think it is a solid start to investigate and unraveling the molecular background of coat patterns. Development of microsatellites for fine-mapping of Tabby and Ticked seems reasonable and so does the genetic linkage mapping.

## Comment 16
Author: [Borttaget]

Strålande. Det förklarar ju den teori Lina tutat i mig som jag också köpte ![Skrattande](http://siames.ifokus.se/tiny3/plugins/emotions/img/smiley-laughing.gif "Skrattande")

Nu vill jag ha forskning på Piebald och White locket!!
